Linear 1 3-diarylpropanoids
Medchemexpress LLC Avobenzone | 70356-09-1 | 98.0% | 100 MG
Avobenzone is a dibenzoylmethane compound widely used as a UVA filter in sunscreens for skin photoprotection. It is also an endocrine disruptor that directly binds to estrogen receptor β and acts as an estrogen agonist.
- Significantly promotes adipogenesis in hBM-MSCs
- Significantly up-regulates mRNA levels of PPARγ during adipogenesis in hBM-MSCs
- Inhibits proliferative activities of human trophoblast cells and induces apoptosis in HTR8/SVneo cells
- Shows weak ERα agonism and weak AR antagonism
Medchemexpress LLC Avobenzone | 70356-09-1 | 98.0% | 5 G
Avobenzone, a dibenzoylmethane compound, is one of the most widely used filters in sunscreens for skin photoprotection in the UVA band. It is also an endocrine disruptor that directly binds to estrogen receptor β and acts as an estrogen agonist.
- Promotes adipogenesis in hBM-MSCs
- Up-regulates mRNA levels of PPARγ during adipogenesis
- Inhibits proliferative activities of human trophoblast cells
- Induces apoptosis in HTR8/SVneo cells
- Shows weak ERα agonism and weak AR antagonism
eMolecules 778-22-3 | 2,2-DIPHENYLPROPANE | AstaTech | MFCD00008794 | 196.293 | C15H16 | 95.000 | CC(C)(c1ccccc1)c1ccccc1 | 1g | 335878684
2,2-DIPHENYLPROPANE | AstaTech | 778-22-3 | MFCD00008794 | 196.293 | C15H16 | 95.000 | CC(C)(c1ccccc1)c1ccccc1 | 1g | 335878684
Selleck Chemical LLC Avobenzone S1904-25mg
Avobenzone (Butyl methoxydibenzoylmethane BF2AVB) is an oil soluble ingredient used in sunscreen products to absorb the full spectrum of UVA rays and a dibenzoylmethane derivative
Selleck Chemical LLC Phlorizin S2343-1g
Phlorizin (Phloridzin) is a dihydrochalcone found in the bark of pear (Pyrus communis) apple cherry and other fruit trees Phlorizin is a non-selective SGLT inhibitor with Ki of 300 nM and 39 nM for hSGLT1 and hSGLT2 respectively Phlorizin is also a Na /K -ATPase inhibitor
Medchemexpress LLC Naringenin chalcone | 73692-50-9 | 50 MG
Naringenin chalcone is an orally active intermediate in flavonol biosynthesis. It induces apoptosis, inhibits the production of MCP-1 and NO, and exhibits anticancer activity against glioblastoma. It also possesses anti-inflammatory and anti-allergic properties.
- Induces apoptosis
- Inhibits the production of MCP-1 and NO
- Exhibits anticancer activity against glioblastoma
- Has anti-inflammatory and anti-allergic properties
Medchemexpress LLC Naringenin chalcone | 73692-50-9 | MFCD00016762 | 100 MG
Naringenin chalcone is an orally active intermediate in flavonol biosynthesis. It induces apoptosis and inhibits the production of MCP-1 and NO. This compound exhibits anticancer activity against glioblastoma and possesses anti-inflammatory and anti-allergic properties. Intended for research use only.
- Induces apoptosis in glioblastoma cells.
- Inhibits production of MCP-1, TNF-α, and NO in macrophages.
- Increases adiponectin mRNA levels and protein secretion in adipocytes.
- Reduces eosinophilic airway inflammation and airway hyperresponsiveness.
- Suppresses Th2 cytokine production and reduces mucus overproduction.
- Reduces tumor volume and weight in glioblastoma xenograft models.
- Increases plasma adiponectin levels in diabetic mice.
- Inhibits anaphylactic response to IgE-mediated passive cutaneous anaphylaxis.
TARGETMOL CHEMICALS INC Naringenin chalcone 10MG
Also available in 1 mg, 2 mg, 5 mg, 25 mg, 50 mg and bulk. Please contact Fisher for quotes. Naringenin chalcone is a natural product isolated from the stem of the plant Machaerium isadelphum (Fabaceae).Naringenin chalcone has anti-inflammatory activity. Purity 98.11%
Medchemexpress LLC PI3K/AKT-IN-1 | 3033069-84-7 | 99.64% | C23H23N5O4S | 1 ML
PI3K/AKT-IN-1 is an effective PI3K/AKT dual inhibitor with IC50 values of 6.99 μM for PI3Kγ, 4.01 μM for PI3Kδ, and 3.36 μM for AKT. It exhibits anticancer activity by inhibiting the PI3K/AKT axis and inducing caspase 3 dependent apoptosis.
- Effective dual inhibitor of PI3K/AKT
- Exhibits anticancer activity
- Inhibits PI3K/AKT axis
- Induces caspase 3 dependent apoptosis
Medchemexpress LLC (E)-naringenin chalcone | 25515-46-2 | MFCD00016762 | 98.9% | 272.26 g/mol | C15H12O5 | 10 MG
(E)-Naringenin chalcone is a flavonoid-derived chalcone supplied for research use. It is described as an orally active anti-allergic agent with reported antioxidant, anti-inflammatory, and anticancer activities. The compound is provided as a light yellow solid with high purity and is intended for laboratory studies and small-molecule assays.
- Orally active anti-allergic agent and antioxidant.
- Reported anti-inflammatory and anticancer activity for research studies.
- Light yellow solid appearance suitable for handling in laboratory assays.
- High purity (~98.9%) for reproducible experimental results.
- Molecular weight 272.26 g/mol; formula C15H12O5.
- Store sealed away from moisture and light; recommended cold storage conditions for solutions.
Medchemexpress LLC Diphenyl-1-pyrenylphosphine | 110231-30-6 | MFCD00278755 | 95.0% | 386.42 g/mol | C28H19P | 25 MG
Diphenyl-1-pyrenylphosphine (DPPP) is a pyrene-based, peroxide-reactive fluorescent probe used to detect hydroperoxides and reactive oxygen species in biochemical assays. Supplied as a solid, it provides sensitive fluorescence readout and is suitable for preparing stock solutions for analytical and cellular studies. Handle protected from light and store at low temperature to preserve stability.
- Fluorescent peroxide-reactive probe for hydroperoxide detection.
- Pyrene-based fluorophore with emission around 380 nm for sensitive readout.
- Supplied as a solid for convenient stock solution preparation.
- High purity (about 95%) appropriate for analytical applications.
- Small packaging ideal for low-volume assays (25 MG).
- Store protected from light and refrigerated to maintain stability.
Selleck Chemical LLC Xanthohumol
Xanthohumol a prenylated chalcone from hop inhibits COX-1 and COX-2 activity and shows chemopreventive effects Xanthohumol inhibits diacylglycerol acyltransferase 1 (DGAT1) and DGAT2 with both IC50 of 40 M Xanthohumol is also a potent antiviral agent against a series of DNA and RNA viruses Xanthohumol induces growth inhibition and apoptosis in cancer cells Phase 1
Medchemexpress LLC Isodecyl diphenyl phosphate | 29761-21-5 | MFCD00072254 | 99.0% | 390.45 g/mol | C22H31O4P | 50mg
Isodecyl diphenyl phosphate (IDPP) is a flame retardant IDPP has an ability to induce DNA damage and exertes S phase cell ratio-reducing effects in A549 cells[1]
Medchemexpress LLC Isodecyl diphenyl phosphate | 29761-21-5 | MFCD00072254 | 390.45 | C22H31O4P | 5mg
Isodecyl diphenyl phosphate (IDPP) is a flame retardant IDPP has an ability to induce DNA damage and exertes S phase cell ratio-reducing effects in A549 cells[1]